Blog | The Rise of Cloning Technology: From Dolly the Sheep to Chimeric Embryos

#

The Rise of Cloning Technology: From Dolly the Sheep to Chimeric Embryos

28 mars 2023

Twitter Facebook Linkedin email

Human cloning is a scientific and ethical topic that has sparked interest and controversy for decades. It is the process of creating a genetically identical copy of a human being. The idea of human cloning has been explored in science fiction for many years, but it was not until the late 1990s that it became a real possibility with the cloning of Dolly the sheep. In this article, we will explore the history of human cloning, the methods used to clone humans, the purposes behind human cloning, and the positives and downsides of this controversial practice.

When did it appear?

The first successful cloning of a mammal occurred in 1996, when scientists at the Roslin Institute in Scotland cloned Dolly the sheep. This groundbreaking achievement opened the door for the possibility of human cloning.  Aldous Huxley’s 1932 novel "Brave New World" depicts a dystopian society in which humans are cloned and conditioned to fit into predetermined roles in society.

Human cloning methods:

There are three main methods of human cloning: reproductive cloning, therapeutic cloning, and DNA cloning.

-Reproductive cloning involves creating an embryo that is genetically identical to a living or deceased individual. This is done by removing the DNA from an egg and replacing it with the DNA from the individual to be cloned. The egg is then stimulated to develop into an embryo, which can be implanted in a surrogate mother’s womb to develop into a fetus and eventually a newborn.

-Therapeutic cloning, also known as somatic cell nuclear transfer, involves creating an embryo that is genetically identical to a living individual for the purpose of harvesting stem cells. These stem cells can be used to treat a variety of medical conditions.

-DNA cloning involves creating a large number of copies of a specific segment of DNA. This method is often used in genetic research to study specific genes.

The purpose of human cloning

The purpose of human cloning has been debated for many years. Supporters of human cloning argue that it could be used to create genetically identical replacement tissues or organs for individual in need of transplants, or to help infertile couples conceive children. Therapeutic cloning could also be used to develop new treatments for diseases such as Parkinson’s, Alzheimer’s, and spinal cord injuries.

Opponents of human cloning argue that it is unethical and could have dangerous consequences. There is concern that human cloning could be used to create an army of identical soldiers or to create a new class of genetically superior humans. There is also the fear that human cloning could lead to physical abnormalities, developmental problems, and other health issues.

Its positives

There are several potential positives to human cloning. One of the most significant is the ability to create replacement tissues and organs for individuals in need of transplants. This could help to reduce the waiting list for organ transplants and could potentially save many lives. Therapeutic cloning could also be used to develop new treatments for diseases that currently have no cure.

Another positive of human cloning is the ability to create a genetically related child for infertile couples. This could be a huge benefit to couples struggling with infertility, and could give them the opportunity to experience the joy of parenthood.

Its downsides

There are also several potential downsides to human cloning. One of the biggest concerns is the ethical and moral implications of creating a human being through cloning. Many people believe that it is wrong to create life in this way, and that it goes against the natural order of things.

There is also concern about the safety of human cloning. There is the fear that cloning could lead to physical abnormalities, developmental problems, and other health issues. There is also the concern that cloning could be used for nefarious purposes, such as creating a new class of genetically superior humans or an army of identical soldiers

exemples from human cloning

There have not been any confirmed examples of human cloning for reproductive purposes, as it is widely considered unethical and illegal in most countries. However, there have been some instances of human cloning for research purposes.

One example is the cloning of human embryos to harvest stem cells for medical research. In 2013, scientists at Oregon Health & Science University announced that they had successfully cloned human embryos to extract stem cells. The researchers stated that this research could lead to new treatments for diseases and conditions such as Parkinson’s, Alzheimer’s, and spinal cord injuries.

Another example of human cloning for research purposes is the creation of “chimeric” embryos, which are created by combining human and animal cells. In 2021, scientists in the United States announced that they had created chimeric embryos by injecting human stem cells into monkey embryos. The researchers stated that this research could help to develop new treatments for a variety of diseases.

While human cloning for reproductive purposes is not currently practiced, the development of new technologies such as CRISPR gene editing has raised concerns about the potential for “designer babies” in the future. Some worry that the ability to genetically engineer human embryos could lead to a new era of eugenics, in which individuals are selected for certain traits or characteristics.

Dolly the sheep.

Dolly the sheep is one of the most famous examples of animal cloning, and her successful cloning in 1996 was a major milestone in the field of biotechnology. Dolly was cloned using the process of somatic cell nuclear transfer, which involves transferring the nucleus of a somatic (non-reproductive) cell into an egg cell that has had its own nucleus removed.

Dolly was cloned from a mammary gland cell taken from an adult sheep, and her birth was announced in 1997. She was the first mammal to be cloned from an adult somatic cell, and her successful cloning opened up new possibilities for using cloning technology in agriculture, medicine, and other fields.

Dolly was created by a team of scientists at the Roslin Institute in Scotland, led by Dr. Ian Wilmut. Her creation involved a complex series of steps, including removing the nucleus from an egg cell, fusing it with a mammary gland cell from an adult sheep, and stimulating the fused cell to divide and develop into an embryo.

Dolly was born after 277 failed attempts, and her successful cloning was a major scientific achievement. However, her creation also sparked ethical concerns about the possibility of cloning humans and the welfare of cloned animals. Dolly herself suffered from a number of health issues, including arthritis and a lung infection, and she was euthanized in 2003 at the age of six due to a progressive lung disease. Despite these concerns, Dolly remains an important symbol of scientific progress and the potential of biotechnology to transform our world. 

Ultimately, the prospect of reproductive human cloning raises many ethical and medical questions. It also touches on deeper theological questions. Perhaps there is nothing more fundamental than this: Does a cloned person have a soul?

Promotion

The Rise of Cloning Technology: From Dolly the Sheep to Chimeric Embryos


^