human reproduction into new territory

12 mars 2023

Scientists in Japan have successfully bred mice with  two fathers, using eggs derived from male cells.

This scientific breakthrough has potential implications for the development of new fertility treatments.

The technique, known as chromosomal engineering, involves reprogramming cells from male mice to lose their "Y chromosome" and develop a second "X chromosome" to provide the XX female contribution. The resulting eggs were then fertilized using mouse sperm and transferred into the uterus of surrogate female mice.

However, the technique still relies on surrogate mothers as scientists have yet to develop an artificial uterus that can ensure proper embryo development in the lab. Although promising, the method's low success rate and ethical implications mean that there is still a long way to go before it can be used in humans.